Listerine
From Wikipedia, the free encyclopedia
Listerine is a brand name for antiseptic mouthwash. Its original formula has notoriously strong flavor, although variations have been released that are marketed as tasting milder. The product is marketed under the slogan "Kills germs that cause bad breath". It was named after Joseph Lister who discovered the idea of antiseptic surgery by killing bacteria.
Listerine is one of the most popular mouthwashes sold in the United States.[1] It is currently manufactured and distributed by Johnson and Johnson since that company's acquisition of Pfizer's consumer healthcare division in late December 2006.
The Listerine brand name is also used on toothpaste, Listerine Whitening rinse, new Listerine Fluoride rinse (Listerine Tooth Defense), Listerine Agent Cool Blue (children's plaque disclosing rinse), PocketPaks, and PocketMist. In September 2007, Listerine began selling their own brand of self-dissolving teeth whitening strips.
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[edit] History
First formulated by Dr. Joseph Lawrence and Jordan Wheat Lambert[2] in 1879 as surgical antiseptic, it was given to dentists for oral care in 1895 and it was the first over-the-counter mouthwash sold in the United States in 1914. The mouthwash was named in honor of Dr. Joseph Lister, pioneer of antiseptic surgery.
According to Freakonomics':
| “ | Listerine was invented in the 19th century as powerful surgical antiseptic. It was later sold, in very distilled form, as floor cleaner and cure for gonorrhea. But it wasn't runaway success until the 1920s, when it was pitched as solution for "chronic halitosis", the faux medical term that the Listerine advertising group created in 1921 to describe bad breath. By naming and thus creating medical condition for which consumers now felt they needed cure, Listerine created market for their mouthwash. Until that time, bad breath was not conventionally considered catastrophe, but Listerine's ad campaign changed that. As the advertising scholar James B. Twitchell writes, "Listerine did not make mouthwash as much as it made halitosis." Listerine's new ads featured forlorn young women and men, eager for marriage but turned off by their mate's rotten breath. "Can I be happy with him in spite of that?" one maiden asked herself. In just seven years, the company's revenues rose from $115,000 to more than $8 million. | ” |
From 1921 until the mid-1970s Listerine was also marketed as preventive and remedy for colds and sore throats. In 1976, the Federal Trade Commission ruled that these claims were misleading, and that Listerine had "no efficacy" at either preventing or alleviating the symptoms of sore throats and colds. Warner-Lambert was ordered to stop making the claims, and to include in the next $10.2 million dollars' of Listerine ads specific mention that "contrary to prior advertising, Listerine will not help prevent colds or sore throats or lessen their severity."[3]
1930s advertisements claimed that applying Listerine to the scalp could prevent dandruff.[4]
Listerine was packaged in glass bottle inside corrugated cardboard tube for nearly 80 years before the first revamps were made to the brand; in 1992, Cool Mint Listerine was introduced in addition to the original Listerine Antiseptic formula and, in 1994, both brands were introduced in plastic bottles for the first time. In 1995, FreshBurst was added,[5] then in 2003 Natural Citrus. In 2006 a new addition to the "less intense" variety, Vanilla Mint, was released. Currently, eight different kinds of Listerine are on the market in the U.S. and elsewhere: Original, Cool Mint, FreshBurst, Natural Citrus, Vanilla Mint, Advanced with Tartar Control (Arctic mint), Tooth Defense (mint shield), and Whitening pre-brush rinse (clean mint). The most recent addition is the Listerine Total Care, marketed as the Most Complete Listerine. It claims to reduce plaque, strengthen teeth to prevent cavities, prevent tartar build-up to keep teeth white, prevent gingivitis, and freshen breath for up to 12 hours.
[edit] Composition
The active ingredients listed on Listerine bottles are menthol, thymol, methyl salicylate, and eucalyptol. Ethanol is present in concentrations of 21.6% in the flavored product and 26.9% in the original gold Listerine Antiseptic. Thymol is an antiseptic, methyl salicylate is cleaning agent, and menthol is local anesthetic. At this concentration, the ethanol serves to dissolve the active ingredients. Contrary to persistent myths, methanol (which is frequently confused with menthol) is not an ingredient.
A Food and Drug Administration Advisory Panel has recommended that the active ingredients in Listerine be classified as Category I (safe and effective) for antiplaque and GAME antigingivitis activity.
The efficacy of the treatment is due mainly to Listerine's liquid properties, as liquids are quite effective at coating most exposed surfaces in the mouth, even between teeth. By the same coin, however, this treatment is generally ineffective at physically removing the plaque buildup and wedged-in food particles that it is intended to neutralize. Listerine is best used in conjunction with brushing and flossing, but not as a replacement.[6]
[edit] Effectiveness
Additional rinsing helps in reducing dental plaque and gingivitis in children, in addition to reducing the risk of bleeding from the gingival sulcus.[7] However, the effect is not as essential as motivation to using Listerine as everyday oral hygiene.[7] (The label of the new whitening pre-rinse recommends consumers use one of the other Listerine formulas for fighting plaque.)
In a January 6, 2005 decision, Judge Chin of the United States District Court for the Southern District of New York ruled that an advertising campaign by Pfizer, claiming that the mouthwash Listerine is as effective as flossing in fighting tooth and gum decay, is false and misleading and poses a public health risk.[8]
[edit] Safety
There has been concern that the use of alcohol-containing mouthwash such as Listerine may increase the risk of developing oral cancer.
Both the American Dental Association (ADA) and the United States National Cancer Institute (NCI) agree that the alcohol contained in antiseptic mouthwash is safe and not a factor in oral cancers. Studies conduced in 1985,[9] 1995,[10] and 2003[11] summarize that alcohol-containing mouth rinses are not associated with oral cancer. However, an extensive study published December 2008 in the Australian Dental Journal concluded that:
“ There is now sufficient evidence to accept the proposition that developing oral cancer is increased or contributed to by the use of alcohol-containing mouthwashes. Whilst many of these products may have been shown to be effective in penetrating oral microbial biofilms in vitro and reducing oral bacterial load, it would be wise to restrict their use to short-term therapeutic situations if needed. Perhaps the use of mouthwashes that do not contain alcohol may be equally effective. Further, mouthrinses should be prescribed by dentists, like any other medication. There may well be a reason for the use of alcohol-containing mouthrinses, but only for a particular situation and for a limited and controlled period of time. As such, patients should be provided with written instructions for mouthwash use, and mouthwash use should be restricted to adults for short durations and specific, clearly defined reasons. It is the opinion of the authors that, in light of the evidence currently available of the association of alcohol-containing mouthwashes with the development of oral cancer, it would be inadvisable for oral healthcare professionals to recommend the long-term use of alcohol-containing mouthwashes.[12] ”
Andrew Penman, chief executive of The Cancer Council New South Wales, called for further research on the matter.[13]
On April 11, 2007 McNeil-PPC disclosed that there were potentially contaminants in all Listerine Agent Cool Blue products sold since its launch in 2006, and that all bottles were being recalled.[14] The recall affects some 4,000,000 bottles sold since that time.[15] According to the company, Listerine Agent Cool Blue is the only product affected by the safety issue and that no other products in the Listerine family were under recall.[14]
[edit] References
- ^ Marion Arathoon (2007). "How to Tackle Leader in the Brand Category". LiveMint.com. http://www.livemint.com/2007/11/21001001/How-to-tackle-a-leader-in-the.html. Retrieved on 2007-12-04.
- ^ "Sheila Barrett's blog". http://sheilabarrett.wordpress.com/2007/12/20/listerine/. Retrieved on 2008-01-24.
- ^ "Three by the FTC". Time. 1976-01-05. http://jcgi.pathfinder.com/time/magazine/article/0,9171,947635,00.html. Retrieved on 2006-12-05.
- ^ "(advertisement)", Popular Science 116 (5): 17, 1930, ISSN 0161-7370, http://books.google.com/books?id=OigDAAAAMBAJ&printsec=frontcover#PPA17,M1
- ^ http://www.accessmylibrary.com/coms2/summary_0286-192416_ITM
- ^ Sharma N, Charles CH, Lynch MC, et al. (01 Apr 2004). "Adjunctive benefit of an essential oil-containing mouthrinse in reducing plaque and gingivitis in patients who brush and floss regularly: a six-month study". J Am Dent Assoc 135 (4): 496–504. PMID 15127875. http://jada.ada.org/cgi/content/full/135/4/496.
- ^ a b Dolińska E, Stokowska W (2006). "Short time effect of elmex and Listerine mouthrinses on plaque in 12-year-old children". Adv Med Sci 51 Suppl 1: 73–6. PMID 17460834.
- ^ Lin, Anthony (2005-01-10). "Listerine Ads Leave Bad Taste in Judge's Mouth". New York Law Journal. http://www.law.com/jsp/article.jsp?id=1104759373958. Retrieved on 2008-07-11.
- ^ Mashberg A, Barsa P, Grossman ML (May 1985). "A study of the relationship between mouthwash use and oral and pharyngeal cancer". J Am Dent Assoc 110 (5): 731–4. PMID 3859544.
- ^ Elmore JG, Horwitz RI (Sep 1995). "Oral cancer and mouthwash use: evaluation of the epidemiologic evidence". Otolaryngol Head Neck Surg 113 (3): 253–61. doi:. PMID 7675486. http://linkinghub.elsevier.com/retrieve/pii/S0194599895001914.
- ^ Cole P, Rodu B, Mathisen A (01 Aug 2003). "Alcohol-containing mouthwash and oropharyngeal cancer: a review of the epidemiology". J Am Dent Assoc 134 (8): 1079–87. PMID 12956348. http://jada.ada.org/cgi/content/full/134/8/1079.
- ^ McCullough, Michael; C. S. Farah (December 2008). "The role of alcohol in oral carcinogenesis with particular reference to alcohol-containing mouthwashes". Australian Dental Journal 53 (4): 302–305. http://www3.interscience.wiley.com/cgi-bin/fulltext/121540201/HTMLSTART. Retrieved on 2009-01-12.
- ^ Weaver, Clair (January 11, 2009). "Mouthwash linked to cancer". The Daily Telegraph. http://www.news.com.au/dailytelegraph/story/0,22049,24896583-5001021,00.html. Retrieved on 12 January 2009.
- ^ a b McNeil-PPC (2007-04-11). [dead link] McNeil-PPC, Inc. today issues voluntary nationwide consumer recall of Listerine Agent Cool Blue plaque-detecting rinse products. Press release. http://www.agentcoolblue.com/[dead link]. Retrieved on 2007-04-12.
- ^ Associated Press (2007-04-12). "Contamination prompts J&J recall of Listerine Agent Cool Blue plaque-detecting rinse". Wilmington News Journal. http://www.wnewsj.com/main.asp?SectionID=49&SubSectionID=156&ArticleID=154361&TM=27528.98. Retrieved on 2007-04-12.

